Abrysvo logo. /Courtesy of Pfizer Korea

Korea Pfizer Pharmaceuticals said on the 14th that the respiratory syncytial virus (RSV) vaccine "Abrysvo" received approval from the Ministery of Food and Drug Safety.

Abrysvo is a bivalent vaccine that uses recombinant prefusion F proteins of RSV A and B as antigens.

When administered to pregnant people at 28–36 weeks of pregnancy, it can protect infants up to 6 months after birth, and people 60 and older and high‑risk groups ages 18–59 are also eligible.

In a phase 3 global clinical trial involving about 7,400 pregnant people, the risk of severe RSV lower respiratory tract disease in infants born to the Abrysvo group was up to 82.4% lower than in the placebo group. In a phase 3 trial involving about 37,000 people ages 60 and older, it reduced the risk of RSV lower respiratory tract disease by 88.9%.

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