LG H&H(051900) said on the 20th that a research paper proving the efficacy of its proprietary technology that delivers the key factor in regulating cellular aging, "NAD+," into the skin was published in the international bioengineering journal Materials Today Bio. The journal is an SCI-grade journal in the bioengineering field.
NAD+ is a substance involved in cellular energy production and has drawn attention as a next-generation anti-aging ingredient, but its molecular structure makes skin absorption difficult and its stability low, limiting its use as a cosmetic raw material.
LG H&H developed "NAD Power24™" through joint research with Professor Ryu Dong-ryeol's team in the Department of Biomedical Science and Engineering at the Gwangju Institute of Science and Technology (GIST) to solve this problem. Instead of the existing method of enclosing NAD+ inside a carrier, the company applied an "ionically bonded modified liposome" technology, binding NAD+ as ions to the surface of the carrier and designing it to flexibly change shape when passing through the skin barrier to boost permeation efficiency.
According to the company, NAD+ delivered deep into the skin by this technology restored the function of mitochondria, which produce cellular energy. It said UV-damaged skin DNA was repaired, the number of senescent cells increased by oxidative stress decreased, and the survival period of skin cells increased from 30 days to 55 days. The company said that when applied to skin tissue from people in their 60s, skin aging indicators recovered to the level of those in their 30s.
LG H&H has also secured related core patents. Kang Nae-gyu, LG H&H chief technology officer (CTO), said, "It is meaningful in that it presents a new 'skin longevity' technology that enhances skin energy and resilience," adding, "We are currently applying it to the development of NAD+-related raw materials and to the Bichup line of the luxury brand The Whoo."