The official cause of death for Eric Dane, an actor from the drama 'Grey's Anatomy,' has been released.

On the 2nd (local time), Page Six reported that according to the death certificate, Grey's Anatomy star Eric Dane died of respiratory failure. His underlying cause of death was the result of amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease).

Eric Dane died on Feb. 19, on the 2nd month after the 10 months since he released the fact of his Lou Gehrig's disease diagnosis. He was 53.

Eric Dane's family said in a statement, "With heavy hearts we announce that Eric Dane passed away Thursday afternoon after a brave battle with Lou Gehrig's disease. During his illness, Eric became a passionate advocate for awareness and research, and he was determined to make changes for others facing the same fight."

The late actor had been candid about his condition, which "is a neurological disease that affects nerve cells in the brain and spinal cord and leads to loss of muscle control."

In an interview with Good Morning America last June, the late Eric Dane said his symptoms first appeared as weakness in his right hand, and "at the time I didn't think it was a big deal. I thought it was from texting too much or that my hand was just tired. But a few weeks later I realized it had gotten a little worse."

At the time of his death, the late Eric Dane was legally married to his estranged wife, Rebecca Gayheart. The two married in 2004 and had two daughters together, but they began living separately seven years ago. They later rescinded their divorce in March 2025.

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